[(5-Chloropentyl)sulfanyl]benzene → N-(3-{1-[5-(Phenylsulfanyl)pentyl]-4-piperidinyl}phenyl)cyclopropanecarboxamide

HRID 1832736Notes

Reaction equation

HRID 1832736 reaction equation
Cl[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][S:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.[NH:14]1[CH2:19][CH2:18][CH:17]([C:20]2[CH:21]=[C:22]([NH:26][C:27]([CH:29]3[CH2:31][CH2:30]3)=[O:28])[CH:23]=[CH:24][CH:25]=2)[CH2:16][CH2:15]1>>[C:8]1([S:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2][N:14]2[CH2:19][CH2:18][CH:17]([C:20]3[CH:21]=[C:22]([NH:26][C:27]([CH:29]4[CH2:30][CH2:31]4)=[O:28])[CH:23]=[CH:24][CH:25]=3)[CH2:16][CH2:15]2)[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

Participants

3

Reactant 2

HCID 13427894[(5-Chloropentyl)sulfanyl]benzeneHCID 22048669N-[3-(4-Piperidinyl)phenyl]cyclopropanecarboxamide

Product 1

HCID 22049102N-(3-{1-[5-(Phenylsulfanyl)pentyl]-4-piperidinyl}phenyl)cyclopropanecarboxamide

Procedure

Prepared by Procedure G and Scheme B1 using [(5-chloropentyl)sulfanyl]benzene and N-[3-(4-piperidinyl)phenyl]cyclopropanecarboxamide: ESMS m/e: 423.1 (M+H)+.

Workup

  1. customPrepared by Procedure G and Scheme B1

Sources & evidence

ORD record
ord-c1946b56335643aaa0ca05b09cb2e655
Source dataset
uspto-grants-2006_06
Patent number
US07067534B1

Reaction notes

Loading…