Methanesulfonyl chloride → HCID 58651324, compound

HRID 1832762Notes

Reaction equation

HRID 1832762 reaction equation
[CH3:1][S:2](Cl)(=[O:4])=[O:3].[NH2:6][C@H:7]([C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1)[CH2:8][CH2:9][N:10]1[CH2:15][CH2:14][CH:13]([C:16]2[CH:17]=[C:18]([NH:22][C:23](=[O:27])[CH:24]([CH3:26])[CH3:25])[CH:19]=[CH:20][CH:21]=2)[CH2:12][CH2:11]1>>[CH3:25][CH:24]([CH3:26])[C:23]([NH:22][C:18]1[CH:19]=[CH:20][CH:21]=[C:16]([CH:13]2[CH2:12][CH2:11][N:10]([CH2:9][CH2:8][C@H:7]([NH:6][S:2]([CH3:1])(=[O:4])=[O:3])[C:28]3[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=3)[CH2:15][CH2:14]2)[CH:17]=1)=[O:27]

Participants

3

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 69523474N-(3-(1-[(3S)-3-amino-3-phenylpropyl]-4-piperidinyl)phenyl)-2-methylpropanamide

Product 1

HCID 58651324HCID 58651324, compound

Procedure

Prepared by Procedure Q1 and Scheme AC using methanesulfonyl chloride and N-(3-{1-[(3S)-3-amino-3-phenylpropyl]-4-piperidinyl}phenyl)-2-methylpropanamide. ESMS m/e: 458.6 (M+H)+.

Workup

  1. customPrepared by Procedure Q1 and Scheme AC

Sources & evidence

ORD record
ord-49ac99d05f0f4dd2bb7f029acb953fc3
Source dataset
uspto-grants-2006_06
Patent number
US07067534B1

Reaction notes

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