2-Nitrophenyl isocyanate → HCID 58651288, compound

HRID 1832775Notes

Reaction equation

HRID 1832775 reaction equation
[N:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[N+:10]([O-:12])=[O:11])=[C:2]=[O:3].[NH2:13][C@H:14]([C:35]1[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=1)[CH2:15][CH2:16][N:17]1[CH2:22][CH2:21][CH:20]([C:23]2[CH:24]=[C:25]([NH:29][C:30](=[O:34])[CH:31]([CH3:33])[CH3:32])[CH:26]=[CH:27][CH:28]=2)[CH2:19][CH2:18]1>>[CH3:32][CH:31]([CH3:33])[C:30]([NH:29][C:25]1[CH:26]=[CH:27][CH:28]=[C:23]([CH:20]2[CH2:19][CH2:18][N:17]([CH2:16][CH2:15][C@H:14]([NH:13][C:2]([NH:1][C:4]3[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=3[N+:10]([O-:12])=[O:11])=[O:3])[C:35]3[CH:36]=[CH:37][CH:38]=[CH:39][CH:40]=3)[CH2:22][CH2:21]2)[CH:24]=1)=[O:34]

Participants

3

Reactant 2

HCID 768342-Nitrophenyl isocyanateHCID 69523474N-(3-(1-[(3S)-3-amino-3-phenylpropyl]-4-piperidinyl)phenyl)-2-methylpropanamide

Product 1

HCID 58651288HCID 58651288, compound

Procedure

Prepared by Procedure P and Scheme AB using 1-isocyanato-2-nitrobenzene and N-(3-{1-[(3S)-3-amino-3-phenylpropyl]-4-piperidinyl}phenyl)-2-methylpropanamide: ESMS m/e: 543.6 (M+H)+.

Workup

  1. customPrepared by Procedure P and Scheme AB

Sources & evidence

ORD record
ord-9889b3944c5d4272819d198d0f990dee
Source dataset
uspto-grants-2006_06
Patent number
US07067534B1

Reaction notes

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