1-Isocyanato-2-(methylsulfanyl)benzene → HCID 58651350, compound

HRID 1832777Notes

Reaction equation

HRID 1832777 reaction equation
[N:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[S:10][CH3:11])=[C:2]=[O:3].[NH2:12][C@H:13]([C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1)[CH2:14][CH2:15][N:16]1[CH2:21][CH2:20][CH:19]([C:22]2[CH:23]=[C:24]([NH:28][C:29](=[O:33])[CH:30]([CH3:32])[CH3:31])[CH:25]=[CH:26][CH:27]=2)[CH2:18][CH2:17]1>>[CH3:31][CH:30]([CH3:32])[C:29]([NH:28][C:24]1[CH:25]=[CH:26][CH:27]=[C:22]([CH:19]2[CH2:18][CH2:17][N:16]([CH2:15][CH2:14][C@H:13]([NH:12][C:2]([NH:1][C:4]3[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=3[S:10][CH3:11])=[O:3])[C:34]3[CH:35]=[CH:36][CH:37]=[CH:38][CH:39]=3)[CH2:21][CH2:20]2)[CH:23]=1)=[O:33]

Participants

3

Reactant 2

HCID 27369891-Isocyanato-2-(methylsulfanyl)benzeneHCID 69523474N-(3-(1-[(3S)-3-amino-3-phenylpropyl]-4-piperidinyl)phenyl)-2-methylpropanamide

Product 1

HCID 58651350HCID 58651350, compound

Procedure

Prepared by Procedure P and Scheme AB using 1-isocyanato-2-(methylsulfanyl)benzene and N-(3-{1-[(3S)-3-amino-3-phenylpropyl]-4-piperidinyl}phenyl)-2-methylpropanamide: ESMS m/e: 545.0 (M+H)+.

Workup

  1. customPrepared by Procedure P and Scheme AB

Sources & evidence

ORD record
ord-74115bd7be154c80a89d87acc5e6d771
Source dataset
uspto-grants-2006_06
Patent number
US07067534B1

Reaction notes

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