Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1832800Generated: October 25, 2026

5-Methyl-3-phenylisoxazole-4-carbonyl chloride → N-(3-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}propyl)-5-methyl-3-phenyl-4-isoxazolecarboxamide

https://huagongshe.com/reaction/1832800

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Methyl-3-phenylisoxazole-4-carbonyl chlorideHCID 85624—
ReactantN-{3-[1-(3-aminopropyl)-4-piperidinyl]phenyl}2-methylpropanamideHCID 16757470—
SolventTetrahydrofuranHCID 8028—
ProductN-(3-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}propyl)-5-methyl-3-phenyl-4-isoxazolecarboxamideHCID 22048939—

Reaction Steps

Prepared by Procedure Q1 (THF) and Scheme AT using N-{3-[1-(3-aminopropyl)-4-piperidinyl]phenyl}-2-methylpropanamide and 5-methyl-3-phenyl-4-isoxazolecarbonyl chloride: ESMS m/e: 489.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07067534B1
Source datasetuspto-grants-2006_06
ORD IDord-077ac7593360464895c54351299b1d2d
Source noteuspto-grants-2006_06