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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1832812Generated: October 31, 2026

2-Naphthoyl chloride → N-(2-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}ethyl)-2-naphthamide

https://huagongshe.com/reaction/1832812

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Naphthoyl chlorideHCID 75246—
ReactantN-(3-[1-(2-aminoethyl)-4-piperidinyl]phenyl)-2-methylpropanamideHCID 16757469—
SolventTetrahydrofuranHCID 8028—
ProductN-(2-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}ethyl)-2-naphthamideHCID 22048924—

Reaction Steps

Prepared by Procedure Q1 (THF) and Scheme AT using N-{3-[1-(2-aminoethyl)-4-piperidinyl]phenyl}-2-methylpropanamide and 2-naphthoyl chloride: ESMS m/e: 444.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07067534B1
Source datasetuspto-grants-2006_06
ORD IDord-9d268131c9e24c58976f9557ebc96877
Source noteuspto-grants-2006_06