HRID1832850

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2723904

4-Methoxyphenylhydrazine hydrochloride

C7H11ClN2O

反应SMILES：CC(C)C(=O)Nc1cccc(C2CCN(CCCCC(=O)c3ccc(C(F)(F)F)cc3)CC2)c1

HCID22049207

未命名化合物

PRODUCTS

产物

反应SMILES：COc1ccc2[nH]c(-c3ccc(C(F)(F)F)cc3)c(CCCN3CCC(c4cccc(NC(=O)C(C)C)c4)CC3)c2c1

HCID22049591

未命名化合物

PROCEDURE

实验过程

Prepared by Procedure E and Scheme M using 2-methyl-N-[3-(1-[5-oxo-5-[4-(trifluoromethyl)phenyl]pentyl}-4-piperidinyl)phenyl]propanamide and 4-methoxyphenylhydrazine hydrochloride: ESMS m/e: 578.2 (M+H)+.

WORKUP

后处理

customPrepared by Procedure E and Scheme M

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-b6f21b133aa44a0380ab09a8372cd0a5
来源数据集: uspto-grants-2006_06
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US07067534B1
来源说明: uspto-grants-2006_06

反应SMILES

[CH3:1][CH:2]([CH3:34])[C:3]([NH:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([CH:12]2[CH2:17][CH2:16][N:15]([CH2:18][CH2:19][CH2:20][CH2:21][C:22](=O)[C:23]3[CH:28]=[CH:27][C:26]([C:29]([F:32])([F:31])[F:30])=[CH:25][CH:24]=3)[CH2:14][CH2:13]2)[CH:7]=1)=[O:4].Cl.[CH3:36][O:37][C:38]1[CH:43]=[CH:42][C:41]([NH:44]N)=[CH:40][CH:39]=1>>[CH3:36][O:37][C:38]1[CH:39]=[C:40]2[C:41](=[CH:42][CH:43]=1)[NH:44][C:22]([C:23]1[CH:28]=[CH:27][C:26]([C:29]([F:31])([F:32])[F:30])=[CH:25][CH:24]=1)=[C:21]2[CH2:20][CH2:19][CH2:18][N:15]1[CH2:14][CH2:13][CH:12]([C:8]2[CH:7]=[C:6]([NH:5][C:3](=[O:4])[CH:2]([CH3:34])[CH3:1])[CH:11]=[CH:10][CH:9]=2)[CH2:17][CH2:16]1