Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1832855Generated: October 26, 2026

4-(Trifluoromethoxy)phenylhydrazine hydrochloride → N-[3-(1-{3-[2-(3-Fluorophenyl)-5-(trifluoromethoxy)-1H-indol-3-YL]propyl}-4-piperidinyl)phenyl]-2-methylpropanamide

https://huagongshe.com/reaction/1832855

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethoxy)phenylhydrazine hydrochlorideHCID 2777328—
ReactantN-(3-{1-[5-(3-Fluorophenyl)-5-oxopentyl]-4-piperidinyl}phenyl)-2-methylpropanamideHCID 22049351—
ProductN-[3-(1-{3-[2-(3-Fluorophenyl)-5-(trifluoromethoxy)-1H-indol-3-YL]propyl}-4-piperidinyl)phenyl]-2-methylpropanamideHCID 22049561—

Reaction Steps

Prepared by Procedure E and Scheme M using N-(3-{1-[5-(3-fluorophenyl)-5-oxopentyl]-4-piperidinyl}phenyl)-2-methylpropanamide and 4-(trifluoromethoxy)phenylhydrazine hydrochloride: ESMS m/e: 582.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07067534B1
Source datasetuspto-grants-2006_06
ORD IDord-619bf8e7e38b47b3b550973ec4fbfce8
Source noteuspto-grants-2006_06