Phenylhydrazine hydrochloride → N-[3-(1-{3-[2-(4-Chlorophenyl)-1H-indol-3-YL]propyl}-4-piperidinyl)phenyl]-2-methylpropanamide

HRID 1832869Notes

Reaction equation

HRID 1832869 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=O)[CH2:9][CH2:10][CH2:11][CH2:12][N:13]2[CH2:18][CH2:17][CH:16]([C:19]3[CH:20]=[C:21]([NH:25][C:26](=[O:30])[CH:27]([CH3:29])[CH3:28])[CH:22]=[CH:23][CH:24]=3)[CH2:15][CH2:14]2)=[CH:4][CH:3]=1.Cl.[C:33]1([NH:39]N)[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[NH:39][C:33]3[C:38]([C:9]=2[CH2:10][CH2:11][CH2:12][N:13]2[CH2:18][CH2:17][CH:16]([C:19]4[CH:20]=[C:21]([NH:25][C:26](=[O:30])[CH:27]([CH3:29])[CH3:28])[CH:22]=[CH:23][CH:24]=4)[CH2:15][CH2:14]2)=[CH:37][CH:36]=[CH:35][CH:34]=3)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 60962Phenylhydrazine hydrochlorideHCID 22048755N-(3-{1-[5-(4-chlorophenyl)-5-oxopentyl]-4-piperidinyl}phenyl)-2-methylpropanamide

Product 1

HCID 22049463N-[3-(1-{3-[2-(4-Chlorophenyl)-1H-indol-3-YL]propyl}-4-piperidinyl)phenyl]-2-methylpropanamide

Procedure

Prepared by Procedure E and Scheme M using N-(3-{1-[5-(4-chlorophenyl)-5-oxopentyl]-4-piperidinyl}phenyl)-2-methylpropanamide and 1-phenylhydrazine hydrochloride: ESMS m/e: 514.2 (M+H)+.

Workup

  1. customPrepared by Procedure E and Scheme M

Sources & evidence

ORD record
ord-77927a1fab3948888ce1f207a6e23ac5
Source dataset
uspto-grants-2006_06
Patent number
US07067534B1

Reaction notes

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