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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1832876Generated: October 30, 2026

4-(Trifluoromethoxy)phenylhydrazine hydrochloride → N-[3-(1-{3-[2-(4-Fluorophenyl)-5-(trifluoromethoxy)-1H-indol-3-YL]propyl}-4-piperidinyl)phenyl]-2-methylpropanamide

https://huagongshe.com/reaction/1832876

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethoxy)phenylhydrazine hydrochlorideHCID 2777328—
ReactantN-(3-{1-(5-(4-fluorophenyl)-5-oxopentyl]-4-piperidinyl}phenyl)-2-methylpropanamideHCID 22049378—
ProductN-[3-(1-{3-[2-(4-Fluorophenyl)-5-(trifluoromethoxy)-1H-indol-3-YL]propyl}-4-piperidinyl)phenyl]-2-methylpropanamideHCID 22049058—

Reaction Steps

Prepared by Procedure E and Scheme M using N-(3-{1-[5-(4-fluorophenyl)-5-oxopentyl]-4-piperidinyl}phenyl)-2-methylpropanamide and 4-(trifluoromethoxy)phenylhydrazine hydrochloride: ESMS m/e: 582.9 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07067534B1
Source datasetuspto-grants-2006_06
ORD IDord-b6879a75e1e24166b199b2a2ae7ae7fb
Source noteuspto-grants-2006_06