9-ethyl-9H-carbazole-3-carbaldehyde → N-(4-{1-[(9-Ethyl-9H-carbazol-3-YL)methyl]-4-piperidinyl}phenyl)butanamide

HRID 1832968Notes

Reaction equation

HRID 1832968 reaction equation
[CH2:1]([N:3]1[C:15]2[CH:14]=[CH:13][C:12]([CH:16]=O)=[CH:11][C:10]=2[C:9]2[C:4]1=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH3:2].[NH:18]1[CH2:23][CH2:22][CH:21]([C:24]2[CH:29]=[CH:28][C:27]([NH:30][C:31](=[O:35])[CH2:32][CH2:33][CH3:34])=[CH:26][CH:25]=2)[CH2:20][CH2:19]1>CC(O)=O>[CH2:1]([N:3]1[C:15]2[CH:14]=[CH:13][C:12]([CH2:16][N:18]3[CH2:23][CH2:22][CH:21]([C:24]4[CH:29]=[CH:28][C:27]([NH:30][C:31](=[O:35])[CH2:32][CH2:33][CH3:34])=[CH:26][CH:25]=4)[CH2:20][CH2:19]3)=[CH:11][C:10]=2[C:9]2[C:4]1=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH3:2]

Participants

4

Reactant 2

HCID 820559-ethyl-9H-carbazole-3-carbaldehydeHCID 21957274N-[4-(4-piperidinyl)phenyl]butanamide

Product 1

HCID 22049441N-(4-{1-[(9-Ethyl-9H-carbazol-3-YL)methyl]-4-piperidinyl}phenyl)butanamide

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Prepared by Procedure F and Scheme R, without HOAc, using 9-ethyl-9H-carbazole-3-carbaldehyde and N-[4-(4-piperidinyl)phenyl]butanamide: ESMS m/e: 454.2 (M+H)+.

Sources & evidence

ORD record
ord-8f92d6aeda1e4cbba69c1a08df84d6df
Source dataset
uspto-grants-2006_06
Patent number
US07067534B1

Reaction notes

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