Benzene, 1-iodo-4-(trifluoromethyl)- → 2-Methyl-N-{3-[1-({1-[4-(trifluoromethyl)phenyl]-1H-indol-5-YL}methyl)-4-piperidinyl]phenyl}propanamide

Participants

Role	Name	HCID	Charge
Reactant	Benzene, 1-iodo-4-(trifluoromethyl)-	HCID 67993	—
Reactant	N-{3-[1-(1H-indol-5-ylmethyl)-4-piperidinyl]phenyl)-2-methylpropanamide	HCID 22049334	—
Product	2-Methyl-N-{3-[1-({1-[4-(trifluoromethyl)phenyl]-1H-indol-5-YL}methyl)-4-piperidinyl]phenyl}propanamide	HCID 22048872	—

Reaction Steps

Prepared by Procedure C and Scheme Q1 with CuBr in place of Cu, using 1-iodo-4-(trifluoromethyl)benzene and N-{3-[1-(1H-indol-5-ylmethyl)-4-piperidinyl]phenyl}-2-methylpropanamide: ESMS m/e: 520.2 (M+H)+.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07067534B1
Source dataset	uspto-grants-2006_06
ORD ID	ord-8723700b28e34927bc9793c473f06231
Source note	uspto-grants-2006_06