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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1832999Generated: October 26, 2026

4-Iodotoluene → 2-Methyl-N-[3-(1-{[1-(4-methylphenyl)-1H-indol-5-YL]methyl}-4-piperidinyl)phenyl]propanamide

https://huagongshe.com/reaction/1832999

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-IodotolueneHCID 12207—
ReactantN-{3-[1-(1H-indol-5-ylmethyl)-4-piperidinyl]phenyl)-2-methylpropanamideHCID 22049334—
Product2-Methyl-N-[3-(1-{[1-(4-methylphenyl)-1H-indol-5-YL]methyl}-4-piperidinyl)phenyl]propanamideHCID 22049369—

Reaction Steps

Prepared by Procedure C and Scheme Q1, with CuBr in place of Cu, using 1-iodo-4-methylbenzene and N-{3-[1-(1H-indol-5-ylmethyl)-4-piperidinyl]phenyl}-2-methylpropanamide: ESMS m/e: 466.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07067534B1
Source datasetuspto-grants-2006_06
ORD IDord-bcaaa0c4e3634d6e8764fa33b99f5733
Source noteuspto-grants-2006_06