Benzene, 1-iodo-3-(trifluoromethyl)- → 2-Methyl-N-{3-[1-({1-[3-(trifluoromethyl)phenyl]-1H-indol-4-YL}methyl)-4-piperidinyl]phenyl}propanamide

Participants

Role	Name	HCID	Charge
Reactant	Benzene, 1-iodo-3-(trifluoromethyl)-	HCID 67868	—
Reactant	N-(3-[1-(1H-indol-4-ylmethyl)-4-piperidinyl]phenyl}-2-methylpropanamide	HCID 22048637	—
Product	2-Methyl-N-{3-[1-({1-[3-(trifluoromethyl)phenyl]-1H-indol-4-YL}methyl)-4-piperidinyl]phenyl}propanamide	HCID 22049512	—

Reaction Steps

Prepared by Procedure C and Scheme Q1, with CuBr in place of Cu, using 1-iodo-3-(trifluoromethyl)benzene and N-{3-[1-(1H-indol-4-ylmethyl)-4-piperidinyl]phenyl}-2-methylpropanamide: ESMS m/e: 520.2 (M+H)+.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07067534B1
Source dataset	uspto-grants-2006_06
ORD ID	ord-d1a83fa9f9a647c9bc697a68dda43bbb
Source note	uspto-grants-2006_06