3-Iodopyridine → HCID 22048781, compound

HRID 1833017Notes

Reaction equation

I[C:2]1[CH:3]=[N:4][CH:5]=[CH:6][CH:7]=1.[NH:8]1[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][C:15]=2[CH2:17][N:18]2[CH2:23][CH2:22][CH:21]([C:24]3[CH:25]=[C:26]([NH:30][C:31](=[O:35])[CH:32]([CH3:34])[CH3:33])[CH:27]=[CH:28][CH:29]=3)[CH2:20][CH2:19]2)[CH:10]=[CH:9]1>>[CH3:34][CH:32]([CH3:33])[C:31]([NH:30][C:26]1[CH:27]=[CH:28][CH:29]=[C:24]([CH:21]2[CH2:20][CH2:19][N:18]([CH2:17][C:15]3[CH:14]=[CH:13][CH:12]=[C:11]4[C:16]=3[N:8]([C:2]3[CH:3]=[N:4][CH:5]=[CH:6][CH:7]=3)[CH:9]=[CH:10]4)[CH2:23][CH2:22]2)[CH:25]=1)=[O:35]

Participants

Reactant 2

HCID 707143-Iodopyridine

HCID 22048591HCID 22048591, compound

Product 1

HCID 22048781HCID 22048781, compound

Procedure

Prepared by Procedure C and Scheme Q1, with CuBr in place of Cu, using 3-iodopyridine and N-{3-[1-(1H-indol-7-ylmethyl)-4-piperidinyl]phenyl}-2-methylpropanamide: ESMS m/e: 453.1 (M+H)+.

Sources & evidence

ORD record: ord-ddc13dbb0e004b9fb7c749ba6aea9fa3
Source dataset: uspto-grants-2006_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07067534B1

Reaction notes

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