2-Bromoacetamide → 2-{3-Chloro-4-[3,3,3-trifluoro-2-hydroxy-1-methyl-2-(5-methyl-pyrazin-2-yl)-propyl]-phenoxy}-acetamide
Reaction equation
[Br:1][CH2:2][C:3](=[O:4])[NH2:5].[Cl:6][c:7]1[cH:8][c:9]([OH:28])[cH:10][cH:11][c:12]1[CH:13]([C:14]([C:15]([F:16])([F:17])[F:18])([c:19]1[n:20][cH:21][c:22]([CH3:25])[n:23][cH:24]1)[OH:26])[CH3:27]>>[CH2:2]([C:3](=[O:4])[NH2:5])[O:28][c:9]1[cH:8][c:7]([Cl:6])[c:12]([CH:13]([C:14]([C:15]([F:16])([F:17])[F:18])([c:19]2[n:20][cH:21][c:22]([CH3:25])[n:23][cH:24]2)[OH:26])[CH3:27])[cH:11][cH:10]1Participants
3
Sources & evidence
- ORD record
- ord-28debb44a4534bb5970a28de529589cd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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