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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1833040Generated: October 30, 2026

Sodium Iodide → N-(3-{1-[6-(4-Fluorophenyl)-6-oxohexyl]-4-piperidinyl}phenyl)-2-methylpropanamide

https://huagongshe.com/reaction/1833040

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium IodideHCID 5238—
ReactantPotassium CarbonateHCID 11430—
Reactant6-Chloro-1-(4-fluorophenyl)hexan-1-oneHCID 11817047—
Reactant2-methyl-N-[3-(4-piperidyl)phenyl]propanamideHCID 16757255—
ProductN-(3-{1-[6-(4-Fluorophenyl)-6-oxohexyl]-4-piperidinyl}phenyl)-2-methylpropanamideHCID 22048616—

Reaction Steps

Prepared by Procedure K and Scheme E using K2CO3 instead of Na2CO3 and NaI instead of KI and 6-chloro-1-(4-fluorophenyl)-1-hexanone and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 439.1 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07067534B1
Source datasetuspto-grants-2006_06
ORD IDord-c1e08ddfda4a494895c117d599cf551a
Source noteuspto-grants-2006_06