4-Methoxyphenol → N-(3-{1-[6-(4-Methoxyphenoxy)-6-phenylhexyl]-4-piperidinyl}phenyl)-2-methylpropanamide

HRID 1833051Notes

Reaction equation

HRID 1833051 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([OH:9])=[CH:5][CH:4]=1.O[CH:11]([C:35]1[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=1)[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][N:17]1[CH2:22][CH2:21][CH:20]([C:23]2[CH:24]=[C:25]([NH:29][C:30](=[O:34])[CH:31]([CH3:33])[CH3:32])[CH:26]=[CH:27][CH:28]=2)[CH2:19][CH2:18]1>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([O:9][CH:11]([C:35]2[CH:36]=[CH:37][CH:38]=[CH:39][CH:40]=2)[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][N:17]2[CH2:22][CH2:21][CH:20]([C:23]3[CH:24]=[C:25]([NH:29][C:30](=[O:34])[CH:31]([CH3:33])[CH3:32])[CH:26]=[CH:27][CH:28]=3)[CH2:19][CH2:18]2)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 90154-MethoxyphenolHCID 22049151N-(3-[1-(6-hydroxy-6-phenylhexyl)-4-piperidinyl]phenyl}-2-methylpropanamide

Product 1

HCID 22049457N-(3-{1-[6-(4-Methoxyphenoxy)-6-phenylhexyl]-4-piperidinyl}phenyl)-2-methylpropanamide

Procedure

Prepared by Procedure A and Scheme AN using 4-methoxyphenol and N-{3-[1-(6-hydroxy-6-phenylhexyl)-4-piperidinyl]phenyl}-2-methylpropanamide: ESMS m/e: 529.6 (M+H)+.

Sources & evidence

ORD record
ord-72efc3ea53b84322b599d93d762e824f
Source dataset
uspto-grants-2006_06
Patent number
US07067534B1

Reaction notes

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