Hydrochloric Acid → N-(3-{1-[6-(4-Fluorophenoxy)-6-phenylhexyl]-4-piperidinyl}phenyl)-2-methylpropanamide

Participants

Reaction Steps

Prepared by Procedure A and Scheme AN using 4-fluorophenol and N-{3-[1-(6-hydroxy-6-phenylhexyl)-4-piperidinyl]phenyl}-2-methylpropanamide: 1H NMR (400 MHz, CDCl3), HCl salt δ 8.05 (s, br, 1H), 7.72–6.70 (m, 13H), 5.06–4.96 (m, 1H), 3.66–3.51 (m, 2H), 3.01–2.82 (m, br, 2H), 2.82–2.57 (m, br, 4H), 2.57–2.34 (m, br, 2H), 2.05–1.78 (m, br; 6H), 1.64–1.52 (m, br, 1H), 1.52–1.16 (m, br, 3H), 1.25 (d, 6H, J=7.2 Hz); ESMS m/e: 517.0 (M+H)+.

Provenance & Evidence