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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1833067Generated: October 27, 2026

2-Fluoro-5-(trifluoromethyl)phenol → N-[3-(1-{6-(4-Chlorophenyl)-6-[2-fluoro-5-(trifluoromethyl)phenoxy]hexyl}-4-piperidinyl)phenyl]-2-methylpropanamide

https://huagongshe.com/reaction/1833067

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-5-(trifluoromethyl)phenolHCID 518888—
ReactantN-(3-{1-(6-(4-chlorophenyl)-6-hydroxyhexyl]-4-piperidinyl}phenyl)-2-methylpropanamideHCID 22049304—
ProductN-[3-(1-{6-(4-Chlorophenyl)-6-[2-fluoro-5-(trifluoromethyl)phenoxy]hexyl}-4-piperidinyl)phenyl]-2-methylpropanamideHCID 22048733—

Reaction Steps

Prepared by Procedure A and Scheme AN using 2-fluoro-5-(trifluoromethyl)phenol and N-(3-{1-[6-(4-chlorophenyl)-6-hydroxyhexyl]-4-piperidinyl}phenyl)-2-methylpropanamide: ESMS m/e: 619.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07067534B1
Source datasetuspto-grants-2006_06
ORD IDord-dc8f69173e2f476d88cd9d23a8d98d93
Source noteuspto-grants-2006_06