Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1833068Generated: October 30, 2026

2-Fluoro-5-(trifluoromethyl)phenol → N-[3-(1-{6-(3-Fluorophenyl)-6-[2-fluoro-5-(trifluoromethyl)phenoxy]hexyl}-4-piperidinyl)phenyl]-2-methylpropanamide

https://huagongshe.com/reaction/1833068

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-5-(trifluoromethyl)phenolHCID 518888—
ReactantN-(3-{1-[6-(3-fluorophenyl)-6-hydroxyhexyl]-4-piperidinyl)phenyl)-2-methylpropanamideHCID 22048989—
ProductN-[3-(1-{6-(3-Fluorophenyl)-6-[2-fluoro-5-(trifluoromethyl)phenoxy]hexyl}-4-piperidinyl)phenyl]-2-methylpropanamideHCID 22049303—

Reaction Steps

Prepared by Procedure A and Scheme AN using 2-fluoro-5-(trifluoromethyl)phenol and N-(3-{1-[6-(3-fluorophenyl)-6-hydroxyhexyl]-4-piperidinyl}phenyl)-2-methylpropanamide: ESMS m/e: 603.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07067534B1
Source datasetuspto-grants-2006_06
ORD IDord-37f34306c39842fa88ab76b81c72bdad
Source noteuspto-grants-2006_06