Hydrochloric Acid → HCID 22048595, compound

Participants

Reaction Steps

Prepared by Procedure A and Scheme AN using 4-methoxyphenol and N-(3-{1-[5-(4-chlorophenyl)-5-hydroxypentyl]-4-piperidinyl}phenyl)-2-methylpropanamide: 1H NMR (400 MHz, CDCl3), HCl salt δ 8.13 (s, br, 1H), 7.72–6.70 (m, 12H), 5.08–4.97 (m, 1H), 3.72 (s, 3H), 3.66–3.50 (m, br, 2H), 3.03–2.82 (br, 2H), 2.80–2.54 (m, br, 4H), 2.53–2.17 (m, br, 2H), 2.08–1.78 (m, br, 6H), 1.65–1.38 (m, br, 2H) 1.25 (d, 6H, J=6.8 Hz). Anal. Calc. for C33H42Cl2N2O3.0.54CH2Cl2: C, 63.80; H, 6.88; N, 4.44. Found: C, 63.84; H, 7.18; N, 4.00. ESMS m/e: 549.1 (M+H)+.

Provenance & Evidence