Hydrochloric Acid → N-(3-{1-[5-(4-Fluorophenoxy)-5-(4-fluorophenyl)pentyl]-4-piperidinyl}phenyl)-2-methylpropanamide

Participants

Reaction Steps

Prepared by Procedure A and Scheme AN using 4-fluorophenol and N-(3-{1-[5-(4-fluorophenyl)-5-hydroxypentyl]-4-piperidinyl}phenyl)-2-methylpropanamide: 1H NMR (400 MHz, CDCl3), HCl salt δ 7.62–6.70 (m, 12H), 5.10–5.00 (m, 1H) 3.71–3.56 (m, br, 2H), 3.04–2.82 (br, 2H), 2.78–2.64 (m, br, 3H), 2.64–2.48 (m, br, 3H), 2.05–1.82 (m, br, 6H), 1.62–1.42 (m, br, 2H), 1.25 (d, 6H, J=6.0 Hz); ESMS m/e: 521.2 (M+H)+.

Provenance & Evidence