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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1833084Generated: October 31, 2026

Hydrochloric Acid → HCID 22049479, compound

https://huagongshe.com/reaction/1833084

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant2-Fluoro-5-(trifluoromethyl)phenolHCID 518888—
ReactantHCID 22049157HCID 22049157—
ProductHCID 22049479HCID 22049479—

Reaction Steps

Prepared by Procedure A and Scheme AN using 2-fluoro-5-(trifluoromethyl)phenol and N-(3-(1-[5-(2-fluorophenyl)-5-hydroxypentyl]-4-piperidinyl}phenyl)-2-methylpropanamide: 1H NMR (400 MHz, CDCl3), HCl salt δ 7.89 (s, br, 1H), 7.72–6.88 (m, 11H), 5.59–5.48 (m, 1H), 3.70–3.48 (br, 2H), 3.05–2.84 (br, 2H), 2.82–2.58 (m, br, 4H), 2.58–2.40 (m, br, 2H), 2.22–1.82 (m, br, 6H), 1.71–1.42 (m, br, 2H), 1.25 (d, 6H, J=6.4 Hz); ESMS m/e: 589.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07067534B1
Source datasetuspto-grants-2006_06
ORD IDord-25164aada3564406bc4dcd8f233546dc
Source noteuspto-grants-2006_06