HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 54486135, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 14964780 | HCID 14964780 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 54486135 | HCID 54486135 | — |
Reaction Steps
A solution of 11 g of t-butyloxycarbonyl-L-prolyl-β-alanine methyl ester in 80 ml of methanol was saturated with ammonia gas at 0° C and stored for 2 days at room temperature. The solution was concentrated in vacuo and the residue crystallised from methanol/water. Yield: 9.8 g; melting point 175°-4 177° C; [α]D25 = -44.5° (c = 1 in dimethylformamide).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04066635 |
| Source dataset | uspto-grants-1978_01 |
| ORD ID | ord-3bbbd0b308304614b99e8419950739d9 |
| Source note | uspto-grants-1978_01 |