Ammonia → HCID 86735324, compound
Reaction equation
Cl[C:2]1[C:7]2[C:8]([CH3:15])=[N:9][C:10]3[N:11]([N:12]=[CH:13][CH:14]=3)[C:6]=2[N:5]=[CH:4][C:3]=1[C:16]([O:18][CH2:19][CH3:20])=[O:17].[NH3:21]>>[NH2:21][C:2]1[C:7]2[C:8]([CH3:15])=[N:9][C:10]3[N:11]([N:12]=[CH:13][CH:14]=3)[C:6]=2[N:5]=[CH:4][C:3]=1[C:16]([O:18][CH2:19][CH3:20])=[O:17]Participants
3
Procedure
By treating the product of Example 10 with ammonia according to the procedure of Example 5, 6-amino-5-methyl-pyrazolo[1,5-a]pyrido[3,2-e]pyrimidine-7-carboxylic acid, ethyl ester is obtained. Treatment of this product with ethanolic hydrochloric acid yields the hydrochloride salt.
Sources & evidence
- ORD record
- ord-49e9d60a16bf4806910413fd5ea3243f
- Source dataset
- uspto-grants-1978_01
- Patent number
- US04066644
Reaction notes
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