HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 12828437, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2-Chloro-1,1-diethoxyethane | HCID 12128 | — |
| Reactant | 3-Methoxyphenethyl alcohol | HCID 78724 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 12828437 | HCID 12828437 | 9.6% |
Reaction Steps
A mixture of 30 g of 3-methoxyphenethyl alcohol, 30 g of chloroacetaldehyde diethyl acetal and 50 ml of concentrated hydrochloric acid was heated at 60°-80° C for 30 minutes, and, after cooling, water was added to the reaction mixture. The resultant oil was extracted into ethyl acetate, rinsed with water and dried. By this procedure was obtained 4.0 g of 1-chloromethyl-6-methoxyisochroman as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04066648 |
| Source dataset | uspto-grants-1978_01 |
| ORD ID | ord-dab187a7b39a461eab12fd3c99b91722 |
| Source note | uspto-grants-1978_01 |