HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → Ethyl 7-[5-(p-fluorophenyl)-2-pentyl]-5-hydroxy-4-methylcoumarin-3-propionate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | Diethyl 2-acetylglutarate | HCID 73915 | — |
| Reactant | 5-[5-(4-Fluorophenyl)pentan-2-yl]benzene-1,3-diol | HCID 20287904 | — |
| Product | Ethyl 7-[5-(p-fluorophenyl)-2-pentyl]-5-hydroxy-4-methylcoumarin-3-propionate | HCID 22765002 | — |
Reaction Steps
Ethyl 7-[5-(p-fluorophenyl)-2-pentyl]-5-hydroxy-4-methylcoumarin-3-propionate is prepared by reaction of 5-[5-(p-fluorophenyl)-2-pentyl]resorcinol, diethyl α-acetylglutarate, and phosphorus oxychloride according to the method of Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04066667 |
| Source dataset | uspto-grants-1978_01 |
| ORD ID | ord-a4242383c0c1408198f8124990b68f9e |
| Source note | uspto-grants-1978_01 |