Acetone → (3-trifluoromethyl-phenoxy)-acetaldehyde

HRID 1833483Notes

Reaction equation

HRID 1833483 reaction equation
C([O:3][CH:4](OCC)[CH2:5][O:6][C:7]1[CH:12]=[CH:11][CH:10]=[C:9]([C:13]([F:16])([F:15])[F:14])[CH:8]=1)C.CC(C)=O.S(=O)(=O)(O)O>O>[F:14][C:13]([F:15])([F:16])[C:9]1[CH:8]=[C:7]([CH:12]=[CH:11][CH:10]=1)[O:6][CH2:5][CH:4]=[O:3]

Participants

5

Reactant 3

HCID 180AcetoneHCID 1118Sulfuric AcidHCID 126618001-(2,2-Diethoxyethoxy)-3-(trifluoromethyl)benzene

Product 1

HCID 11252687(3-trifluoromethyl-phenoxy)-acetaldehyde

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 3-trifluoromethylphenoxyacetaldehyde diethyl acetal (146.3 g.; 0.527 mole), acetone (600 ml.), water (550 ml.), and concentrated sulfuric acid (3.5 ml.) is heated under reflux for 22 hours.

Workup

  1. temperatureis heated
  2. temperatureunder reflux for 22 hours

Sources & evidence

ORD record
ord-41503a40f42e469cb9498a80a725c331
Source dataset
uspto-grants-1978_01
Patent number
US04066675

Reaction notes

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