2(5H)-Thiazolone, 4-amino- → HCID 178509023、化合物

HRID 1833499ノート

反応式

HRID 1833499 の反応式
[NH:1]=[C:2]1[CH2:6][S:5][C:4](=[O:7])[NH:3]1.[NH:8]=[C:9]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:11](=N)[NH:10]1>CO>[NH:8]=[C:9]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:11](=[C:6]2[S:5][C:4](=[O:7])[NH:3][C:2]2=[NH:1])[NH:10]1

参加物

4

反応物 2

HCID 1373471612(5H)-Thiazolone, 4-amino-HCID 178508669HCID 178508669、化合物

生成物 1

HCID 178509023HCID 178509023、化合物

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

A mixture of 3.5 parts of 4-imino-2-thiazolidinone, 4.4 parts of 1,3-diiminoisoindoline and 100 parts of methanol was stirred under an atmosphere of nitrogen at room temperature for three hours and then at reflux temperature for two hours. The reaction mixture was cooled to 25° C and the solid therein was collected by filtration, washed with fresh methanol and dried in vacuo at 50° C to obtain 5.4 parts of 1-imino-3-(2-oxo-4-imino-5-thiazolidinylidene)isoindoline as a yellow powder melting at 346°-348° C (dec).

後処理

  1. temperatureat reflux temperature for two hours
  2. temperatureThe reaction mixture was cooled to 25° C
  3. filtrationthe solid therein was collected by filtration
  4. washwashed with fresh methanol
  5. customdried in vacuo at 50° C

出典と根拠

ORDレコード
ord-1f5115ee6f774fe08cccafc44ece26c3
出典データセット
uspto-grants-1978_01
特許番号
US04066653

反応ノート

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