2-Piperidino-4-imino-2-thiazoline hydrochloride → 2,3-dihydro-1H-isoindole hydrochloride

HRID 1833509Notes

Reaction equation

HRID 1833509 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][C:10]=1Cl)[C:7](=N)[NH:6][C:5]2=N.Cl.C1(CCCCCNC2SCC(=N)N=2)C=CC=CC=1.Cl.N1(C2SCC(=N)N=2)CCCCC1>>[ClH:1].[CH2:5]1[C:4]2[C:8](=[CH:9][CH:10]=[CH:2][CH:3]=2)[CH2:7][NH:6]1

Participants

4

Reactant 3

HCID 162452962-Piperidino-4-imino-2-thiazoline hydrochlorideHCID 178479110HCID 178479110, compoundHCID 178508677HCID 178508677, compound

Product 1

HCID 123110312,3-dihydro-1H-isoindole hydrochloride

Procedure

Following the procedure described in Example 9, part B above but using equivalent amount of 5,6-dichloro-1,3-diiminoisoindoline and 2-(5-phenylpentylamino)-4-imino-2-thiazoline hydrochloride in place of the 1,3-diiminosioindoline and 2-piperidino-4-imino-2-thiazoline hydrochloride respctively, there is obtained as the product 1-imino-5,6-dichloro-3-[2-(5-phenylpentylamino)-4-imino-2-thiazolin-5-ylidene[isoindoline hydrochloride.

Sources & evidence

ORD record
ord-a3b649b639fb4fb980c1cb7a7c84d282
Source dataset
uspto-grants-1978_01
Patent number
US04066653

Reaction notes

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