Sodium Azide → HCID 178527658, compound

HRID 1833540Notes

Reaction equation

HRID 1833540 reaction equation
[K].[S:2]([CH2:6][NH:7][C:8](=[S:11])SC)([OH:5])(=[O:4])=[O:3].[N-:12]=[N+:13]=[N-:14].[Na+]>O>[S:2]([CH2:6][N:7]1[C:8]([SH:11])=[N:14][N:13]=[N:12]1)([OH:5])(=[O:4])=[O:3]

Participants

4

Reactant 2

HCID 33557Sodium AzideHCID 86735065HCID 86735065, compound

Product 1

HCID 178527658HCID 178527658, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 45.3 g. (0.19 mol) of methyl sulfomethyldithiocarbamate potassium salt and 16.9 g. (0.26 mol) of sodium azide in 425 ml. of water was heated at 80° C. for 4.75 hours. The reaction mixture was passed through an Amberlite IR-120H ion exchange resin column and eluted with water until the pH of the eluant became 3.5. The eluant was extracted with ether and the aqueous solution was evaporated to dryness to give 1-sulfomethyltetrazole-5-thiol. The disodium salt is prepared using sodium methoxide-methanol in isopropanol. 1-Sulfomethyltetrazole-5-thiol sodium salt was precipiated and was collected by filtration.

Workup

  1. additionA mixture of 45.3 g
  2. washeluted with water until the pH of the eluant
  3. extractionThe eluant was extracted with ether
  4. customthe aqueous solution was evaporated to dryness

Sources & evidence

ORD record
ord-46b6b1332a6c47e99b7575999d3f9737
Source dataset
uspto-grants-1978_01
Patent number
US04066762

Reaction notes

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