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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1833735Generated: October 30, 2026

HCID 21388868, compound → 2-(4-Pentylphenyl)pyrimidine-5-carbonitrile

https://huagongshe.com/reaction/1833735

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 21388868HCID 21388868—
CatalystZincHCID 23994—
Solvent1,4-DioxaneHCID 31275—
Product2-(4-Pentylphenyl)pyrimidine-5-carbonitrileHCID 13574824—

Reaction Steps

6.3 G. of 4-chloro-5-cyano-2-(4-n-pentylphenyl)-pyrimidine are reacted in 290 ml. of 50% dioxane with 25.3 g. of pre-treated zinc dust and worked up after the reaction in a manner analogous to that described in Example 13. There is obtained 5-cyano-2-(4-n-pentylphenyl)-pyrimidine as colorless crystals having a melting point of 96.0°-96.2° C. and clearing point of 109.0° C. The substance is identical with the compound obtained according to Example

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04066570
Source datasetuspto-grants-1978_01
ORD IDord-8c7eecc8efec494fb092525d85f43c90
Source noteuspto-grants-1978_01