HCID 21388819, compound → HCID 21388815, compound

HRID 1833737Notes

Reaction equation

HRID 1833737 reaction equation
Cl[C:2]1[C:7]([C:8]#[N:9])=[CH:6][N:5]=[C:4]([C:10]2[CH:15]=[CH:14][C:13]([CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])=[CH:12][CH:11]=2)[N:3]=1>[Zn].O1CCOCC1>[C:8]([C:7]1[CH:2]=[N:3][C:4]([C:10]2[CH:15]=[CH:14][C:13]([CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])=[CH:12][CH:11]=2)=[N:5][CH:6]=1)#[N:9]

Participants

4

Reactant 1

HCID 21388819HCID 21388819, compound

Product 1

HCID 21388815HCID 21388815, compound

Reagents, catalysts & solvents 2

HCID 23994ZincCatalystHCID 312751,4-DioxaneSolvent

Procedure

5.7 G. of 4-chloro-5-cyano-2-(4-n-hexylphenyl)-pyrimidine are reacted in 250 ml. of 50% dioxane with 21.9 g. of pre-treated zinc dust and worked up after the reaction in a manner analogous to that described in Example 13. There is obtained 5-cyano-2-(4-n-hexylphenyl)-pyrimidine as colorless crystals having a melting point of 86.3°-87.8° C. (smectic); nematic at 101.3° C; clearing point 102.6°-103.2° c. The substance is identical with the compound obtained according to Example 10.

Workup

  1. customafter the reaction in a manner analogous to

Sources & evidence

ORD record
ord-7ff83d30ba89411cb077070f9ea4d9aa
Source dataset
uspto-grants-1978_01
Patent number
US04066570

Reaction notes

Loading…