HCID 21388785, compound → 5-Cyano-2-(4-n-hexyloxyphenyl)-pyrimidine

HRID 1833748Notes

Reaction equation

HRID 1833748 reaction equation
Cl[C:2]1[C:7]([C:8]#[N:9])=[CH:6][N:5]=[C:4]([C:10]2[CH:15]=[CH:14][C:13]([O:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])=[CH:12][CH:11]=2)[N:3]=1>[Zn].O1CCOCC1>[C:8]([C:7]1[CH:6]=[N:5][C:4]([C:10]2[CH:15]=[CH:14][C:13]([O:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])=[CH:12][CH:11]=2)=[N:3][CH:2]=1)#[N:9]

Participants

4

Reactant 1

HCID 21388785HCID 21388785, compound

Product 1

HCID 213888565-Cyano-2-(4-n-hexyloxyphenyl)-pyrimidine

Reagents, catalysts & solvents 2

HCID 23994ZincCatalystHCID 312751,4-DioxaneSolvent

Procedure

3.0 G. of 4-chloro-5-cyano-2-(4-n-hexyloxyphenyl)-pyrimidine are reacted in 125 ml. of 50% dioxane with 11.0 g. of pre-treated zinc dust and worked up after the reaction in manner analogous to that described in Example 13. There is obtained 5-cyano-2-(4-n-hexyloxyphenyl)-pyrimidine as colorless crystals having a melting point of 93.5°-93.8° C. (smectic); nematic at 121.2° C; clearing point 134.0° C.

Workup

  1. customafter the reaction in manner analogous to

Sources & evidence

ORD record
ord-06dfabd8c3d54d608c1ee9c80434302a
Source dataset
uspto-grants-1978_01
Patent number
US04066570

Reaction notes

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