HCID 54222676, compound → HCID 28689661, compound

Participants

Reaction Steps

22.2 g (0.1 mol) of 3-nitrophenyl-acetic acid isopropylamide were dissolved in 150 ml of ethanol and hydrogenated under a hydrogen pressure of 40-50 atmospheres in the presence of Raney nickel at 50°-60° C. When the reaction had finished, the catalyst was filtered off, the filtrate was concentrated by evaporation under reduced pressure and the residue which remained was recrystallized from petroleum ether. 17.5 g (91% of theory) of 3-amino-phenylacetic acid isopropyl-amide of melting point 93°-95° C were obtained.

Provenance & Evidence