o-Xylyl bromide → HCID 12939246, compound

Participants

Reaction Steps

A mixture of 2-methylbenzyl bromide [prepared as described by Radziszewaki and Wispek, Ber, 15, 1747 (1882); 18.5 g.], methyl 2-furoate (15.3 g.) and anhydrous ferric chloride (0.3 g.) in dry carbon tetrachloride (25 ml.) was heated on a steam bath under reflux for 18 hours and then distilled to give crude methyl 5-(2-methylbenzyl)-2-furoate (7.7 g.) in the form of a pale brown coloured oil, b.p. 120°-145° C./0.1 mm.Hg, suitable for use as a starting material in procedures hereinafter described.

Provenance & Evidence