4-Toluenesulfonyl chloride → HCID 21387572, compound

Participants

Reaction Steps

(±) 1-(2,3-Dichlorophenyl)-1-(2-furyl)ethanol (92 g.) was heated on a steam bath in pyridine (250 ml.) containing p-toluenesulphonyl chloride (69 g.) for 1 hour. The solution was poured into ice water (1 liter) and extracted with diethyl ether (5 × 500 ml.). The combined ethereal extracts were washed with water (2 × 500 ml.), dried over sodium sulphate, filtered and evaporated to give a dark oil, which was distilled to give 1-(2,3-dichlorophenyl)-1-(2-furyl)ethylene as a pale yellow liquid (46 g.), b.p. 140°-180° C./20 mm.Hg.

Provenance & Evidence