反应详情

30 gm (0.103M) ethyl-o-nitrophenylacetylacetoacetate was added over a period of 15-20 minutes to a saturated ammoniacal ethanol solution (prepared by bubbling NH3 gas into 400 cc. absolute for 15-20 minutes while cooling the solution to 0°-5° C.). The orangy mixture was stirred for 1 hour at 5°-10° C. and then left in the refrigerator overnight. The ethyl-γ-2-nitrophenylacetoacetate crystals formed were filtered and dried in vacuum. Additional solid was obtained after evaporation of the filtrate and washing with water to remove any amide formed.

1. customprepared
2. customby bubbling NH3 gas into 400 cc
3. temperatureabsolute for 15-20 minutes while cooling the solution to 0°-5° C.)
4. waitleft in the refrigerator overnight