4-(Methylsulfonyl)phenol → HCID 70614627, compound

HRID 1833936Notes

Reaction equation

HRID 1833936 reaction equation
[CH3:1][S:2]([C:5]1[CH:10]=[CH:9][C:8]([OH:11])=[CH:7][CH:6]=1)(=[O:4])=[O:3].[CH2:12]([O:19][C:20]1[CH:29]=[CH:28][C:23]([O:24][CH2:25][CH2:26][NH2:27])=[CH:22][CH:21]=1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[CH3:1][S:2]([C:5]1[CH:10]=[CH:9][C:8]([O:11][CH2:7][CH:8]([OH:11])[CH2:9][NH:27][CH2:26][CH2:25][O:24][C:23]2[CH:22]=[CH:21][C:20]([O:19][CH2:12][C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=3)=[CH:29][CH:28]=2)=[CH:7][CH:6]=1)(=[O:3])=[O:4]

Participants

3

Reactant 2

HCID 1233504-(Methylsulfonyl)phenolHCID 15034331HCID 15034331, compound

Product 1

HCID 70614627HCID 70614627, compound

Procedure

Reaction of the chlorohydrin derivative of 4-(methylsulfonyl)phenol with p-benzyloxyphenoxyethylamine in accordance with the procedure of Example 15 provides 3-[4-(METHYLSULFONYL)PHENOXY]-1-[(p-BENZYLOXYPHENOXYETHYL)AMINO]-2-PROPANOL.

Sources & evidence

ORD record
ord-efb9971a53b54d5da9ac0b34f194eeea
Source dataset
uspto-grants-1978_01
Patent number
US04067904

Reaction notes

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