反应详情

A solution of α-t-butoxycarbonylamino-m-aminophenylacetic acid (2.66 g, 0.01 mol) and potassium cyanate (0.81 g, 0.01 mol) in a mixture of water (35 ml) and acetic acid (2.5 ml) was heated at 56° for 3 hours. The solution was cooled, acidified with 40% H3PO4, and extracted with ethyl acetate. The dried extracts were evaporated to give the title product: mp 93°-95° (dec).

1. temperaturewas heated at 56° for 3 hours
2. temperatureThe solution was cooled
3. extractionextracted with ethyl acetate
4. customThe dried extracts were evaporated