Hydrochloric Acid → HCID 19746158, compound

Participants

Reaction Steps

A solution of 10 g. of 3-phenoxypyridine in 10 ml. of 2-propanol is treated with an excess of a solution of dry hydrogen chloride in 2-propanol. The resulting solution is stirred and diluted with ether to give a yellow oil. The oil is separated, triturated several times with ether to give 3-phenoxypyridine hydrochloride as a crystalline solid; m.p. 112°-113.5° C. after recrystallization from 2-propanolether followed by drying at reduced pressure.

Provenance & Evidence