Acetate → HCID 131711020, compound

Participants

Reaction Steps

The corresponding spirobenzoxazinium iodide (Example 1) (1.36 g., 0.0025 mole) is dissolved in 50% aqueous acetic acid (200 ml) and passed down a column of Dowex-1 × 2 acetate resin. The first 350 ml. that is collected is evaporated to dryness. The residue is crystallized from ethanolether (1:100) to obtain 3,3-dimethyl-3,4-dihydro-6-(1,1-dimethylethyl)-8-iodospiro[2H-1,3-benzoxazinium-2,1'-cyclohexane]acetate hemihydrate (0.8 g.), m.p. 159°-160° (dec).

Provenance & Evidence