3-(Dimethylamino)propyl chloride hydrochloride → HCID 54353912, compound

HRID 1834050Notes

Reaction equation

HRID 1834050 reaction equation
Cl.[CH3:2][N:3]([CH2:5][CH2:6][CH2:7]Cl)[CH3:4].[N+:9]([C:12]1[O:13][C:14]2[C:26]([C:27]([OH:29])=[O:28])=[CH:25][CH:24]=[CH:23][C:15]=2[C:16]=1[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)([O-:11])=[O:10]>>[N+:9]([C:12]1[O:13][C:14]2[C:26]([C:27]([O:29][CH2:7][CH2:6][CH2:5][N:3]([CH3:4])[CH3:2])=[O:28])=[CH:25][CH:24]=[CH:23][C:15]=2[C:16]=1[C:17]1[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=1)([O-:11])=[O:10]

Participants

3

Reactant 2

HCID 943083-(Dimethylamino)propyl chloride hydrochlorideHCID 20330199HCID 20330199, compound

Product 1

HCID 54353912HCID 54353912, compound

Procedure

Using the method illustrated in Example 25 N,N-dimethylamino-3-chloropropane hydrochloride is reacted with 2-nitro-3-phenyl-7-benzofurancarboxylic acid to provide N,N-dimethylaminopropyl 2-nitro-3-phenyl-7-benzofurancarboxylate, m.p. 65.5°-67.5° C., as a yellow solid.

Sources & evidence

ORD record
ord-fec1e7d327e2419282e71cf39ae9ee6f
Source dataset
uspto-grants-1978_01
Patent number
US04067993

Reaction notes

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