Dichloromethane → HCID 70617081, compound

Participants

Reaction Steps

To 100 ml. of dichloromethane were added 4.2 g. of cephaloglycin monohydrate, 3.0 g. of anhydrous magnesium sulfate, and 2.1 ml. of triethylamine and after stirring the mixture for one hour at room temperature, magnesium sulfate was filtered off to provide a dichloromethane solution of cephaloglycin triethylamine salt. The solution was cooled to -30° C. and then 1.75 g. of 4-oxo-4H-thiopyran-3-carbonyl chloride and 2.1 ml. of triethylamine were added to the solution followed by stirring for one hour.

Provenance & Evidence