N,N-Dimethyl-1,3-propanediamine → HCID 70627548, compound

HRID 1834096Notes

Reaction equation

HRID 1834096 reaction equation
Cl[C:2]1[N:7]=[C:6]([NH:8][CH2:9][CH:10]([O:12][CH:13]([CH3:15])[CH3:14])[CH3:11])[C:5]([N+:16]([O-:18])=[O:17])=[C:4]([CH3:19])[CH:3]=1.[CH3:20][N:21]([CH2:23][CH2:24][CH2:25][NH2:26])[CH3:22]>>[CH3:20][N:21]([CH2:23][CH2:24][CH2:25][NH:26][C:2]1[N:7]=[C:6]([NH:8][CH2:9][CH:10]([O:12][CH:13]([CH3:15])[CH3:14])[CH3:11])[C:5]([N+:16]([O-:18])=[O:17])=[C:4]([CH3:19])[CH:3]=1)[CH3:22]

Participants

3

Reactant 2

HCID 7993N,N-Dimethyl-1,3-propanediamineHCID 21388540HCID 21388540, compound

Product 1

HCID 70627548HCID 70627548, compound

Procedure

5.75 parts of 6-chloro-2-isopropoxypropylamino-4-methyl-3-nitropyridine, 5 parts of dimethylaminopropylamine and 20 parts of alcohol are heated at 90° to 100° C for 12 hours. The excess amine and alcohol are distilled off in vacuo and the residue is extracted with chloroform. After distilling off the solvent from the chloroform solution, 6-dimethylaminopropylamino-2-isopropoxypropylamino-4-methyl-3-nitropyridine is obtained as a yellow substance.

Workup

  1. distillationThe excess amine and alcohol are distilled off in vacuo
  2. extractionthe residue is extracted with chloroform
  3. distillationAfter distilling off the solvent from the chloroform solution

Sources & evidence

ORD record
ord-dc13502b5ce24f65981d23592d85faaa
Source dataset
uspto-grants-1978_01
Patent number
US04068085

Reaction notes

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