Hydrochloric Acid → HCID 178527421, compound

Participants

Reaction Steps

The reagent CF3SO2CH2MgCl was prepared from 22.0 g. (0.15 mole) of methyl perfluoromethylsulfone and 0.2 mole of methylmagnesium chloride in tetrahydrofuran. Butyryl chloride (30.0 g.; 0.3 mole) was added at room temperature and the mixture stirred for two hours. The mixture was hydrolyzed with 3 N HCl, the tetrahydrofuran phase separated and heated to remove solvent. The residue was dissolved in diethyl ether and the solution (dried over MgSO4) heated to remove the ether, giving 14 g. of the novel fluoroalkylsulfonyl methane precursor, CF3SO2CH2COC3H7 b.p. 90° C. (5 mm.). A sample was recrystallized from water, m.p. 67.5°-68.5° C.

Provenance & Evidence