HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[2-(3-Bromophenyl)propyl]-2-(cyclohexylmethyl)piperidine → 2,6-Dichlorobenzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[2-(3-Bromophenyl)propyl]-2-(cyclohexylmethyl)piperidine | HCID 12805099 | — |
| Reactant | HCID 13409096 | HCID 13409096 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 2,6-Dichlorobenzaldehyde | HCID 6737 | — |
Reaction Steps
2-Cyclohexylmethyl-1-{2-[3-(α-hydroxy-2,6-dichlorobenzyl)phenyl]propyl}piperidine (yellow oil) prepared by reaction of 18.9 g. (0.05 mole) of 2-cyclohexylmethyl-1-[2-(3-bromophenyl)-propyl]piperidine with 0.1 mole of butyl lithium in diethyl ether followed by 19.2 g. (0.11 mole) of 2,6-dichlorobenzaldehyde to give 19.3 g. of product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04069256 |
| Source dataset | uspto-grants-1978_01 |
| ORD ID | ord-79510472b67f420db07d26455b1d2f9e |
| Source note | uspto-grants-1978_01 |