1,3-Dibromo-5,5-dimethylhydantoin → 7-Bromo-3 beta,25-dibenzoyloxycholest-5-ene

Participants

Reaction Steps

To a boiling solution of 2.02 gm. of 3β,25-dibenzoyloxycholest- 5-ene (3.3 mmole) in 90 ml. of hexane, and 720 mg. (2.52 mmole) of dibromo-dimethylhydantoin. Reflux for 30 minutes, cool to room temperature, filter and wash with 2 ml. of carbontetrachloride. Concentrate the combined filtrate to dryness to obtain the title product. (2.3 gm.)

Provenance & Evidence