Sodium Hydroxide → HCID 12264816, compound

HRID 1834307Notes

Reaction equation

HRID 1834307 reaction equation
CC[O:3][C:4]([C:6]([NH:8][C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([O:15][CH3:16])[C:10]=1[C:17]([NH2:19])=[O:18])=[O:7])=[O:5].[OH-].[Na+]>O>[CH3:16][O:15][C:11]1[C:10]([C:17]([NH2:19])=[O:18])=[C:9]([NH:8][C:6]([C:4]([OH:5])=[O:3])=[O:7])[CH:14]=[CH:13][CH:12]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 198325Wy 16,922

Product 1

HCID 12264816HCID 12264816, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

2'-Carbamoyl-3'-methoxyoxanilic acid ethyl ester (1.33 g., 0.005 mole) is stirred in 50 ml. water, and 5.0 ml. of N NaOH is slowly added, giving a solution. After 1/2 hour the solution is filtered, and the filtrate is acidified to pH 2 with N HCl, giving 0.71 g. of the title compound, m.p. 214°-215° C., after crystallization from ethanol.

Workup

  1. customgiving a solution
  2. filtrationAfter 1/2 hour the solution is filtered
  3. customgiving 0.71 g
  4. customof the title compound, m.p. 214°-215° C., after crystallization from ethanol

Sources & evidence

ORD record
ord-9e702e157a68436d9173840773552f70
Source dataset
uspto-grants-1978_01
Patent number
US04069343

Reaction notes

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